Technology

Stabilize & Explore

Screen and select

Generate pathology-like target

Validate your target

Stabilize & Explore

Screen and select

Generate pathology-like target

Validate your target

Stabilize & Explore

Native and Structural Stabilization

  Solubilize membrane protein
  Maintain membrane protein stability

Gain : Generate primary hits and leads candidates​

Screen & Select

Conformational Stabilization in Pathology-like conformation

  Perform selective screening
  Generate leads specific to one or several conformational states

Gain : Increase efficacy and selectivity of your hits and leads candidates​

Generate pathology-like target

stabilized in the desired environment

  Stabilized pathology-like target in bicelles or nanodiscs.
  Use antigen for immunization and antibody selection

Gain : Select the best candidates according to the physiopathology

Validate your target

and profile your drug candidates

  Validate membrane protein as target
  Confirm specificity

Gain : Confirm your mechanism of action and the pharmacological profile of drug and antibody candidates

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